There has been a lot of discussion by government
representatives, media, and public health experts about flattening the curve to
limit the strain on health care services during the COVID-19 pandemic. The discussion
surrounding flattening the curve dates back to about 2007 (link)
and the original CDC chart is reproduced below. Additional history about the
evolution of this chart to a recent animated gif by can be found at this link.
While the concept of flattening the curve is simple, the
general public is being bombarded with graphical representation of the
ever-increasing cumulative number of COVID-19 cases around the world and in
their own countries. Here are several immediate examples of tracking sites on
the internet with graphs plotting the total cumulative cases from around the
world.
Usually, the main graphic image is a line graph or histogram
showing the changing total number of COVID-19 cases by day. Technically, this
type of graph is referred to as an ogive, a graph that display cumulative data
usually over a period of time.
Cumulative Frequency Graph (Ogive)
An ogive is a graphic presentation of incrementally
increasing cumulative data usually over periods of time. This kind of graph is
mostly used to depict progress to specific goal or end point. For example, if a
company sets a target goal of selling 10,000 units starting in January how low
long will it take for sales to reach the 10,000-unit threshold. The graph below
shows that monthly sales surpassed the goal of 10,000 units in August.
Another example might be a charity trying to raise $8000 for
new playground equipment for a youth center, as depicted in the graph below. In
this graph the x-axis is not time, but the remaining distance to achieve the
goal of $8000.
Now consider an ogive, a cumulative frequency graph, of
COVID-19 cases below which is from KFF,
a non-profit organization concerned with national health issues. It shows the
cumulative growth of COVID-19 cases through MARCH 24, 2020. But is such an
ogive curve appropriate for a disease outbreak? By using an ogive, do we have
some set goal of the number of COVID-19 cases we are purposefully trying to
reach? A million cases? 10 million cases? No, of course not.
At the beginning of a disease outbreak, a cumulative
frequency graph can reinforce the public message that the outbreak could get
worse. The COVID-19 outbreak did get worse and it evolved into a pandemic. At
this stage of the pandemic the cumulative frequency graph of COVID-19 cases has
lost it informative powers. Everyone is already aware that that cases are
continuing to grow. There is no other message that it conveys.
A distinctive feature of an ogive is that it can never go
down. From a pandemic perspective, even after people stop being infected, the
graph will never go down nor will it go back to zero. Thus, when public health
officials talk about flattening the curve, they are not talking about an ogive
of COVID-19 cases that is prominently displayed across the internet. These
officials are talking about flattening the epidemic curve.
Epidemiological Curve
An epidemiological curve, often referred to as an epidemic
curve, is a graphical representation of the frequency of new cases over time
based on the date of onset of disease, usually depicted as a histogram. Epidemic
curve are always graphed against time. A true epidemic curve is a plot of the
number of new daily case based on date of symptom onset. The significant
difference between an ogive of COVID-19 cases and an epidemic curve is that
only new cases are plotted on a daily basis, not the new cases
plus the total of all the cases that occurred before that date.
Below is an epidemic curve for the United State Center for
Disease Control and Prevention (CDC). From the low number of plotted cases in
the graph, it should be obvious that the CDC does not have onset dates for
the vast majority of US COVID-19 case. The graph notes that the number of daily
new cases from the past few days will change because onset of symptoms can
occur from a few hours to several days before the case is confirmed and added
to the tabulation. In terms creating the graph, onsets dates almost always
happen in the past.
The most significant information component of an epidemic
graph is that an inflection point in the curve is almost immediately
identifiable. The inflection point is
the point in time when the number of cases stops increasing and begins to
decreases. When public health officials talk about flattening the curve, they
are referring to implementing interventions that will reduce the overall shape
of the epidemic curve, particularly at the inflection point, by reducing the
maximum number of daily cases based on onset of symptoms.
Comparison of an Ogive with an Epidemic Graph
The graph below plots both a cumulative frequency of cases
against a number new daily cases. Based on the discussions above, it should be
clear as noted on the chart that the line graph of the cumulative frequency
graph will never go down.
Even though the general public does not have access to the symptom
onset dates of confirmed cases, a psuedo-epidemic graph can be constructed from
available data. Rather than plotting cases by onset dates, a pseudo-epidemic curve
can be graphed based on the number of newly reported cases on a
given day. Such a graph is a reasonable approximation of the underlying
epidemic curve.
The comparison of the ogive and the epidemic curve presented
above is not hypothetical. It is the cumulative daily total of COVID-19 cases
plotted against the pseudo-epidemic graph of the daily new COVID-19 cases for
the Republic of Korea (South Korea) as shown in the full labelled graph below. What
the epidemic graph or curve clearly shows is that about March 2, 2020, South
Korea passed an inflection point and the number of COVID-19 cases starts to
decline. Through aggressive intervention South Korea was able to flatten the
curve during the first few days of March when the number of new cases started
to decline. South Korea is currently on its way to economic and social
recovery.
While ogives, cumulative frequency graphs, of the COVID-19 pandemic
serve to present dazzling graphics - some static and some animated - it is
epidemic curves that will shows the true progress of the disease in a
particular country or the world as a whole. That is the curve that needs to be
flattened.
Note: The South Korea data in the epidemic graph above was obtained from DS4C: Data Science for COVID-19 in South Korea.
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